The ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial
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The ROAM/EORTC-1308 trial: Radiation versus Observation following surgical resection of Atypical Meningioma: study protocol for a randomised controlled trial
BACKGROUND Atypical meningiomas are an intermediate grade brain tumour with a recurrence rate of 39-58 %. It is not known whether early adjuvant radiotherapy reduces the risk of tumour recurrence and whether the potential side-effects are justified. An alternative management strategy is to perform active monitoring with magnetic resonance imaging (MRI) and to treat at recurrence. There are no r...
متن کاملRadiotherapy versus observation following surgical resection of atypical meningioma (the ROAM trial).
Kaur et al 1 have produced a timely systematic review on the role of adjuvant radiotherapy for atypical meningioma (AM) and malignant meningioma. Their review highlights the paucity of good quality prospective studies and the urgent need for prospective clinical trials for AM. Kaur et al 1 identify extent of resection (EOR) as an important prognostic factor but fail to comment on how this was d...
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ژورنال
عنوان ژورنال: Trials
سال: 2015
ISSN: 1745-6215
DOI: 10.1186/s13063-015-1040-3